[1]刘子钰,邓 格,王菲迪,等.慢性束缚应激对小鼠痛经的影响[J].国外医学医学地理杂志,2019,(02):124-125,130.[doi:10.3969/j.issn.1001-8883.2019.02.007]
 LIU Ziyu,DENG Ge,WANG Feidi,et al.Effects of chronic restraint stress on dysmenorrhea in mice[J].Foreign Medical Sciences (Section of Medgeography),2019,(02):124-125,130.[doi:10.3969/j.issn.1001-8883.2019.02.007]
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慢性束缚应激对小鼠痛经的影响()
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国外医学医学地理杂志[ISSN:1001-8883/CN:61-1102/R]

卷:
期数:
2019年02期
页码:
124-125,130
栏目:
基础医学
出版日期:
2019-07-02

文章信息/Info

Title:
Effects of chronic restraint stress on dysmenorrhea in mice
作者:
刘子钰1邓 格1王菲迪1丰凯月1李泽雨1樊同祥1孙晓明2胡 浩2李 帆2
(西安交通大学医学部:1.2015级侯宗濂医学实验班; 2.基础医学实验教学中心,陕西西安 710061)
Author(s):
LIU Ziyu1DENG Ge1WANG Feidi1FENG Kaiyue1LI Zeyu1FAN Tongxiang1SUN Xiaoming2HU Hao2LI Fan2
(1.Grade 2015 Hou Zonglian Medical Class; 2.Basic Medical Experiment Teaching Center,Xi’an Jiaotong University,Xi’an 710061,China)
关键词:
慢性束缚应激 痛经 扭体实验
Keywords:
chronic restraint stress dysmenorrhea writhing test
分类号:
R339
DOI:
10.3969/j.issn.1001-8883.2019.02.007
文献标志码:
A
摘要:
目的 探究慢性心理应激对痛经的影响,旨在对痛经的缓解提出心理层面的针对性建议。方法 将12只雌性小鼠随机分成对照组和慢性应激组,对慢性应激组采用慢性束缚方式诱导慢性心理应激; 再对慢性应激组和对照组小鼠建立痛经模型,通过扭体实验判断其痛经发生情况。结果 对照组和慢性应激组之间扭体潜伏期、扭体次数均存在显著差异(P=0.042<0.05,P=0.012<0.05),慢性应激组扭体潜伏期更短,扭体次数更多。结论 慢性心理应激可加重模型小鼠的痛经程度。
Abstract:
Objective To explore the effects of chronic restraint stress on dysmenorrhea in mice and put forward targeted suggestions on the psychological level to alleviate dysmenorrhea.Methods 12 female mice were randomly divided into control group and chronic stress group.Chronic psychological stress was induced by chronic restraint in chronic stress group,and then dysmenorrhea model was established in chronic stress group and control group,and dysmenorrhea was judged by writhing experiment.Results There were significant differences in the latency and times of writhing between the control group and the chronic stress group(P=0.042<0.05,P=0.012<0.05).The latency of writhing was shorter and the times of writhing were more in the chronic stress group.Conclusion Chronic psychological stress can aggravate dysmenorrhea.

参考文献/References:


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备注/Memo

备注/Memo:
收稿日期:2019-01-25 修回日期:2019-02-28
通信作者:李帆,实验师.
作者简介:刘子钰(1997-),女(汉族),2015级侯宗濂医学实验班在读.
更新日期/Last Update: 2019-07-02