[1]贾 丽.超声弹性及断层成像对甲状腺良恶性病变的诊断价值[J].国外医学医学地理杂志,2019,(02):178-181.[doi:10.3969/j.issn.1001-8883.2019.02.023]
 JIA Li.Diagnostic value of ultrasound elastography and tomographyin benign and malignant thyroid lesions[J].Foreign Medical Sciences (Section of Medgeography),2019,(02):178-181.[doi:10.3969/j.issn.1001-8883.2019.02.023]
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超声弹性及断层成像对甲状腺良恶性病变的诊断价值()
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国外医学医学地理杂志[ISSN:1001-8883/CN:61-1102/R]

卷:
期数:
2019年02期
页码:
178-181
栏目:
技术方法研究
出版日期:
2019-07-02

文章信息/Info

Title:
Diagnostic value of ultrasound elastography and tomographyin benign and malignant thyroid lesions
作者:
贾 丽
(甘肃省庆阳市人民医院超声医学科,甘肃庆阳 745000)
Author(s):
JIA Li
(Department of ultrasound medicine,Qingyang people’s hospital,Qingyang 745000,China)
关键词:
超声弹性成像 断层成像 甲状腺良恶性病变
Keywords:
ultrasound elastography tomography benign and malignant thyroid lesions
分类号:
R581
DOI:
10.3969/j.issn.1001-8883.2019.02.023
文献标志码:
A
摘要:
目的 探究超声弹性及断层成像对甲状腺良恶性病变的诊断价值。方法 选择2015年1月至2018年1月本院接受治疗的98例(121个结节)甲状腺结节患者为研究对象,分别对其实施超声弹性成像及计算机断层成像检查,以病理学检测结果为金标准,评估两种单独检测及联合检测对良恶性甲状腺结节评估的敏感度、特异度、准确度并进行对比,同时以病理检查结果为标准,将结节区分为良性组(75个)和恶性组(46个),对比两种结节超声弹性检查时弹性评分及SR值的差异。结果 ①超声弹性成像对甲状腺结节良恶性鉴别一致性为86.78%,灵敏度为86.96%,特异度为86.67%,阳性预测值为80.00%,阴性预测值为91.55%; ②计算机断层成像对甲状腺结节良恶性病变鉴别的一致性为75.21%,灵敏度为67.39%,特异度为80.00%,阳性预测值为67.39%,阴性预测值为80.00%; ③联合检测对甲状腺良恶性结节鉴别的一致性为92.56%,灵敏度为93.48%,特异度为92.00%,阳性预测值为80.00%,阴性预测值为91.55%; ④对比发现联合检测鉴别的一致性、灵敏度、特异度均高于两种单独检测方式; ⑤分析显示恶性病变结节弹性评分及SR值均明显高于良性结节(P<0.05)。结论 相比于计算机断层成像,超声弹性成像对甲状腺结节良恶性病变具有更好的鉴别价值,同时弹性评分及SR值可作为评估甲状腺结节良恶性病变指标,但仍建议联合应用超声弹性成像及计算机断层成像技术实施鉴别。
Abstract:
Objective To investigate the diagnostic value of ultrasound elasticity and tomography for benign and malignant thyroid lesions.Methods 98 patients(121 nodules)with thyroid nodules who were treated in our hospital from Jan.2015 to Jan.2018 were enrolled in the study.Ultrasound elastography and computed tomography were performed respectively.The pathological test results were used as the gold standard.To evaluate the sensitivity,specificity and accuracy of two separate and combined tests for the assessment of benign and malignant thyroid nodules.In contrast,the results of pathological examination was used as the standard,and the nodules were divided into benign group(75)and malignant group(46).The differences in elasticity score and SR value between the two nodules were compared.Results ①The consistency of ultrasound elastography for the differentiation of benign and malignant thyroid nodules was 86.78%,the sensitivity was 86.96%,the specificity was 86.67%,the negative predictive value was 91.55%,and the positive predictive value was 80.00%.②The consistency of computed tomography in the differential diagnosis of benign and malignant thyroid nodules was 75.21%,the sensitivity was 67.39%,the specificity was 80.00%,the negative predictive value was 80.00%,and the positive predictive value was 67.39%.③The consistency of the joint detection for the differentiation of benign and malignant thyroid nodules was 92.56%,the sensitivity was 93.48%,the specificity was 92.00%,the positive predictive value was 80.00%,and the negative predictive value was 91.55%.④The consistency,sensitivity and specificity of the combined detection were higher than the two separate detection methods.⑤The analysis showed that the malignant lesions nodule elasticity score and the SR scores were significantly higher than the benign nodules(P<0.05).Conclusion Compared with computed tomography,ultrasound elastography has a better value in the differential diagnosis of benign and malignant thyroid nodules.At the same time,the elasticity score and SR value can be used as indicators to evaluate benign and malignant lesions of thyroid nodules.However,it is still recommended to use ultrasound elastography together.Computerized tomography technology is used to identify.

参考文献/References:


[1] Yoon JH,Han K,Kim EK,et al.Diagnosis and management of small thyroid nodules:a comparative study with six guidelines for thyroid nodules[J].Radiology,2017,283(2):560-569.
[2] 张艳,罗渝昆,张明博,等.超声造影周边环状增强对甲状腺结节鉴别诊断的意义[J].中华医学超声杂志,2016,13(1):31-35.
[3] 兰霞斌,张浩.《2015美国甲状腺学会成人甲状腺结节与分化型甲状腺癌诊治指南》外科治疗更新解读[J].浙江医学,2016,54(5):172-176.
[4] 赵海云,刘海霞,佟威,等.甲状腺结节超声应变弹性成像定量分析对结节良恶性的判断价值[J].海南医学院学报,2016,22(11):1179-1181.
[5] 谢强,雷海花,丁淑敏,等.甲状腺结节病变的CT诊断与分析[J].中国创新,2015,12(4):109-112.
[6] 宋江虹,马建军,朱巧梅,等.某三甲医院在职医护人员甲状腺结节流行病学调查研究[J].山西医科大学学报,2014,45(4):278-280.
[7] 杨道玲,韦嘉,张勇,等.实时剪切波超声弹性成像对健康成人肝组织硬度定量分析研究[J].中国超声医学杂志,2014,30(5):411-414.
[8] Benvenga S,Antonelli A,Vita R.Thyroid nodules and thyroid autoimmunity in the context of environmental pollution[J].Rev Endocr Metab Disord,2015,16(4):319-430.
[9] 陈晓华.甲状腺结节性疾病超声弹性成像误诊原因分析[J].中国民族民间医药,2016,25(6):173-175.
[10] 徐兰,赵霞娟,刘婵娟,等.上海市老年男性甲状腺结节性疾病流行病学及发展规律[J].中国老年学,2016,36(7):1722-1724.
[11] 王帅,徐辉雄,徐军妹,等.甲状腺结节微钙化、粗大钙化及环状钙化与甲状腺癌的相关性分析[J].影像诊断与介入放射学,2015,24(3):212-215.
[12] 佘颖,孙德胜,霍宏,等.常规超声联合超声弹性成像在诊断甲状腺占位性病变中的应用价值[J].海南医学院学报,2014,20(3):424-426.
[13] 李向珍,敖萍萍.超声弹性成像在甲状腺癌诊断中的应用价值[J].医学综述,2015,21(14):2672-2673.
[14] 赵炎斌,刘方舟,张园,等.超声弹性成像及CT检查对术前甲状腺肿物性质判断的相关性研究[J].东南大学学报(医学版),2014,33(3):296-299.
[15] 梁笑,王余广,张立春,等.超声弹性成像应变率比值与多层螺旋CT对于老年人甲状腺结节样病变的诊断价值[J].中国老年学杂志,2014,34(17):4801-4802.

备注/Memo

备注/Memo:
收稿日期:2019-01-23 修回日期:2019-02-25
作者简介:贾丽(1980-),女(汉族),大学本科.研究方向:超声医学.
更新日期/Last Update: 2019-07-02